Use this url to cite publication: https://hdl.handle.net/20.500.12512/89378
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Oxidative stress related biomarkers in aged-related human studies on vitamin intervention and healthy aging cohorts / Eugene Jansen, Piet Beekhof, Johannes Cremers, Abdonas Tamosiunas
Type of publication
Konferencijų tezės nerecenzuojamame leidinyje / Conference theses in non-peer-reviewed publication (T2)
Author(s)
Jansen, Eugène H.J.M. | National Institute for Public Health and the Environment, Bilthoven, The Netherlands |
Beekhof, Piet K. | Laboratory for Health Protection research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands |
Cremers, Johannes W.J.M. | Laboratory for Health Protection Research, National Institute for Public Health and the Environment, Bilthoven, The Netherlands |
Title
Oxidative stress related biomarkers in aged-related human studies on vitamin intervention and healthy aging cohorts / Eugene Jansen, Piet Beekhof, Johannes Cremers, Abdonas Tamosiunas
Publisher (trusted)
Oxygen Club of California. University of Turin
Date Issued
2012-06-20
Extent
p. 121.
Is part of
Oxidants and Antioxidants in Biology: Cell Signaling and Nutrient - Gene Interactions : Book of Abstracts : 20-23 June 2012, Alba, Italy / Oxygen Club of California. University of Turin ; Organizers: Giuseppe Poli, Maret G. Traber ; Scientific advisory committee: Enrique Cadenas et al. Torino : Oxygen Club of California. University of Turin, 2012.
Version
Originalus / Original
Series/Report no.
Posters.
Field of Science
Abstract
Oxidative stress and redox status have been related to many chronic diseases and ageing. To test whether biomarkers of oxidative stress really can describe the underlying pathological processes, large-scale screening is recommended in epidemiological cohorts. In addition many components of the oxidation and antioxidant system must be determined simultaneously to obtain an overall view of these processes. In this study we present an automated method for the determination of a large set of biomarkers of both oxidative processes and antioxidant status, which is suitable for large-scale screening. The following processes with representative biomarkers can be measured in large series: lipid peroxidation, protein oxidation, glycation, inflammation, tissue toxicity, iron status, total antioxidant status, anti oxidant enzymes and general serum antioxidants. The auto-analyser used for the measurements of oxidative stress and antioxidant biomarkers is the LX-20 Pro (Beckman-Coulter). The kits used on this auto-analyser are from various companies and have been adjusted to the format of analyzer. Applications will be shown of an age-related biomarker study of a strategic intervention study with multivitamin and mineral supplements (SOR/340006) and of a European cohort study on Health and Aging (CHANCES, EC-FP7).
Type of document
type::text::conference output::conference proceedings::conference paper
Other Identifier(s)
(LSMU ALMA)990000794510107106
Coverage Spatial
Italija / Italy (IT)
Language
Anglų / English (en)