Comparison of physical-chemical and technological properties of microcapsules with lavender essential oil, obtained by various methods
Author | Affiliation | |
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National University of Pharmacy, Kharkiv, Ukraine | ||
Ruban, Olena | National University of Pharmacy, Kharkiv, Ukraine | |
Lietuvos sveikatos mokslų universitetas | National University of Pharmacy, Kharkiv, Ukraine |
Date |
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2022-11-24 |
Bibliogr.: p. 11-12
Introduction. Microencapsulation is the innovative and prospective technique that is used in cosmetology, aromology, agriculture, food, and textile industry [1-2]. Recently, microencapsulation has found a wide application in the pharmaceutical industry. This technique is used for stabilizing of the unstable preparations, such as vitamins, antibiotics, vaccines, serums, enzymes etc.; taste and odor masking of medicinal substances; conversion of liquids into dry flowable products; combination of non-combinable components in one medicine, regulation of release rate and targeted delivery of actives to a particular part of GIT [3]. One of important uses of microencapsulation is the preservation and loss prevention of volatile aromatic compounds, including essential oils [2, 5]. Today, up to 90% of aromatic substances encapsulation is performed by spray-drying method, 5 to 10% by freeze-drying, 2 to 3% by melt extrusion, and 2% by melt injection. Other types of microencapsulation account for less than 1% [4]. Aim of the study. Comparison of physical-chemical and technological properties of microcapsules with Lavender essential oil (LO), obtained by spray-and freeze-drying methods. Methods and objects of the study. The object of the research is microcapsules with LO (SAFC Supply Solutions, Germany). As incapsulating agents Maltodextrin (MD) with DE (7-13) (QinHuangDao LiHua Starch Co., Ltd, China) and Gum Arabic (GA) (Nexira, France) were used. Three emulsion samples with 30% polymer content were prepared, where the amount of MD and GA varied in the following ratios: №1 - 15:15, №2 - 11.25:18.75, №3 - 18.75:11.25, respectively. The amount of LO was constant and was 7.5 g per 100 mL of emulsion. [...].